A simple, sensitive and economic spectrophotometric method has been developed for simultaneous determination of Eperisone hydrochloride and Diclofenac sodium in a pharmaceutical formulation. In the proposed method, the absorbances were measured at 261.0 nm and 275.0 nm corresponding to the absorbance maxima of Eperisone hydrochloride and Diclofenac sodium in Dist. Water respectively. Linearity range was observed in the concentration range of 3–24 μg/ml for Eperisone hydrochloride and 5-40 μg/ml for Diclofenac sodium. Concentration of each drug was obtained by using the absorptivity values calculated for both drugs at two wavelengths, 261.0 nm and 275.0 nm and solving the simultaneous equation. The method was validated statistically and recovery study was performed to confirm the accuracy of the method. The method was found to be rapid, simple, accurate and precise.
Loading....